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Open Access Research

Long-term biochemical results after high-dose-rate intensity modulated brachytherapy with external beam radiotherapy for high risk prostate cancer

Pedro J Prada13*, Lucia Mendez1, José Fernández2, Herminio González1, Isabel Jiménez1 and Elisabeth Arrojo1

Author Affiliations

1 Department of Radiation Oncology, Hospital Universitario Central de Asturias, Oviedo, Spain

2 Department of Radiation Physics, Hospital Universitario Central de Asturias, Oviedo, Spain

3 Department of Radiation Oncology, Hospital Central de Asturias, C/Julian Claveria s/n, Oviedo 33006, (Asturias), Spain

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Radiation Oncology 2012, 7:31  doi:10.1186/1748-717X-7-31

Published: 7 March 2012

Abstract

Background

Biochemical control from series in which radical prostatectomy is performed for patients with unfavorable prostate cancer and/or low dose external beam radiation therapy are given remains suboptimal.

The treatment regimen of HDR brachytherapy and external beam radiotherapy is a safe and very effective treatment for patients with high risk localized prostate cancer with excellent biochemical control and low toxicity.