Audiological findings in patients treated with radio- and concomitant chemotherapy for head and neck tumors

doi:10.1186/1748-717X-4-53

Radiation Oncology

Volume 4

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Dell'Aringa AH
Isaac ML
Arruda GV
Esteves MC
Dell'Aringa AR
Júnior JL
Rodrigues AF

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Isaac ML
Arruda GV
Esteves MC
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Rodrigues AF
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Audiological findings in patients treated with radio- and concomitant chemotherapy for head and neck tumors

Ana Helena B Dell'Aringa¹ , Myrian L Isaac² , Gustavo V Arruda³ , Maria Carolina BN Esteves¹ , Alfredo Rafael Dell'Aringa¹ , José Luis S Júnior⁴ and Alexandre F Rodrigues⁵

¹Departament of Otorhinolaryngology of FAMEMA's General Hospital, Marília, Sao Paulo, Brazil

²Departament of Otorhinolaryngology of FMUSP- RP, Ribeirao Preto, Sao Paulo, Brazil

³Departament of Oncology, Radiotherapy of FAMEMA's General Hospital, Marília, Sao Paulo, Brazil

⁴FAMEMA, Marília, Sao Paulo, Brazil

⁵Marília, Sao Paulo, Brazil

author email corresponding author email

Radiation Oncology 2009, 4:53doi:10.1186/1748-717X-4-53


Published:	15 November 2009

Abstract

Objective

To evaluate the functionality of the auditory system in patients who underwent radiotherapy and chemotherapy treatment with cisplatin to treat head and neck tumors.

Study Design

Case series with planned data collection.

Setting

From May 2007 to May 2008 by the Department of Otorhinolaryngology and the Department of Oncology/Radiotherapy at Faculdade de Medicina de Marília.

Subjects and Methods

Audiological evaluation (Pure Tone Audiometry (air and bone conduction), Speech Audiometry, Tympanometry, Acoustic Reflex testing and Distortion Product Otoacoustic Emissions) was performed in 17 patients diagnosed with head and neck neoplasia and treated with chemotherapy, using cisplatin, and radiotherapy.

Results

12 left ears (70.5%) and 11 right ears (64.7%) presented bilateral decreased hearing soon after the treatment for the frequency 1 kHz (mild auditory damage) and for the frequency 8 kHz (more significant auditory damage).

Conclusion

Patients with head and neck cancer submitted to the conventional radiotherapy treatment, combined with the chemotherapy with cisplatin, presented a high incidence of decreased hearing by the end of treatment. Strong evidence was observed linking auditory alteration to the amount of radiotherapy treatment.